Vaccine and adjuvant design for emerging viruses
نویسندگان
چکیده
منابع مشابه
Emerging respiratory viruses: challenges and vaccine strategies.
The current threat of avian influenza to the human population, the potential for the reemergence of severe acute respiratory syndrome (SARS)-associated coronavirus, and the identification of multiple novel respiratory viruses underline the necessity for the development of therapeutic and preventive strategies to combat viral infection. Vaccine development is a key component in the prevention of...
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Knowledge of the atomic resolution structures of viruses can be a powerful tool for vaccine discovery and design. X-ray crystallography has long served as an invaluable method for virus structure determination at high resolution, but over the past decade, cryoelectron microscopy (cryo-EM) has begun to emerge as a complementary method that can also provide this kind of information. Crystallograp...
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1 Unit for Laboratory Animal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA 2 Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI, USA 3 Center for Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, MI, USA 4 Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, MI...
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The threat of influenza A and B variants via antigenic drift and emerging novel influenza A and B strains in the human population via antigenic shift has spurred research efforts to improve upon current seasonal influenza vaccines. In recent years, a wave of novel technological breakthroughs has lead to the identification of many broadly anti-influenza hemagglutinin (HA) monoclonal antibodies (...
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ژورنال
عنوان ژورنال: Bioengineered Bugs
سال: 2011
ISSN: 1949-1018,1949-1026
DOI: 10.4161/bbug.2.3.15367